Week 5 kicked off with a bang as the 49ers edged out the Rams 26–23 in a Thursday night thriller. Despite Matthew Stafford’s brilliance, San Francisco’s late surge stole the show. With that game setting the tone, we’ve spotlighted 10 offensive players primed to deliver standout performances as the rest of Week 5 unfolds.

Stefon Diggs, WR, New England Patriots

Patriots wideout Stefon Diggs has been nothing short of remarkable just a season after his ACL injury. Against the Panthers, he put up 101 yards on six catches, showing flashes of his old dominance. At this pace, he’s already challenging DeMario Douglas for the starting role. His return has given New England’s offense a much-needed spark and a trusted target.

Romeo Doubs, WR, Green Bay Packers

Romeo Doubs made the most of his chances against the Buccaneers. His five receptions went for 52 yards, but what stood out was his ability to turn three of them into touchdowns. That efficiency highlighted his red zone chemistry with Jordan Love. Doubs didn’t need volume to dominate, proving he can be deadly when the ball comes his way.

Bucky Irving, RB, Tampa Bay Buccaneers

In a tough loss to Philadelphia, Bucky Irving still managed a highlight night. His 72-yard touchdown reception marked his second 70-plus-yard score of the year. He added 63 rushing yards on 15 carries and caught all five of his targets for 102 yards. Irving’s versatility kept Tampa Bay’s offense alive and showcased his ability to impact both the ground and air attack.

Trey McBride, TE, Arizona Cardinals

Trey McBride has turned into the Cardinals’ most dependable option through four weeks. Leading the team in target share, he’s delivered three standout receiving games already. His mix of steady hands and explosive playmaking has set him apart as the go-to target. Arizona’s offense runs through him now, showing he can handle being the centerpiece of a passing attack.

D.K. Metcalf, WR, Pittsburgh Steelers

DK Metcalf finally had his breakout moment with Pittsburgh in Week 4. Facing Minnesota, he racked up 126 yards on five receptions, highlighted by an 80-yard touchdown. That kind of production reminded fans why the Steelers invested in him. His performance balanced the offense, proved his big-play ability, and came at the perfect time with injuries testing the roster.

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Emeka Egbuka, WR, Tampa Bay Buccaneers

Drafted 19th overall, Emeka Egbuka was expected to ease into a loaded Buccaneers offense. Instead, he has become the centerpiece of their rookie class, leading all first-years with 282 receiving yards. From a two-touchdown debut to a 77-yard score against Philadelphia, his knack for game-changing plays has already been critical to Tampa Bay’s success.

Kyren Williams, RB, Los Angeles Rams

Kyren Williams keeps proving he’s the heartbeat of the Rams’ offense. No running back has matched his efficiency on the ground, and his consistency has been unmatched through the first weeks. Fresh off a new contract, he continues to perform at an Offensive Player of the Year level. Los Angeles’ rise is being powered by Williams’ ability to carry the attack.

George Pickens, WR, Dallas Cowboys

George Pickens stepped up in the absence of CeeDee Lamb, putting on a star performance against his defenders. He made eight catches for 134 yards and scored two touchdowns, including a tough sideline grab at the 1-yard line in double coverage. That effort showed his ability to be a true number-one target, giving the Cowboys reliability and explosiveness when needed.

Amon-Ra St. Brown, WR, Detroit Lions

Amon-Ra St. Brown stayed automatic in Week 4, catching all seven of his targets from Jared Goff for 70 yards and two touchdowns. He’s now scored in three straight games, racking up six touchdowns total, the second-most through four games in franchise history. His connection with Goff keeps driving Detroit’s offense, making him one of the most consistent playmakers early.

James Cook, RB, Buffalo Bills

James Cook is backing up his new contract with steady production. He rushed for 117 yards and a touchdown on 22 carries, becoming the first Bills player to score in eight straight games. That score gave Buffalo the lead over Washington and highlighted his reliability. With 284 yards on the season, Cook is proving worth every bit of his extension.

Michael Penix Jr, QB, Atlanta Falcons

Michael Penix Jr. put together his best performance yet, completing 20 of 26 passes for a career-high 313 yards. He guided Atlanta to a win over Washington, evening the team’s record at 2-2. Head coach Raheem Morris awarded him the game ball afterward. With a QBR of 90.5, Penix showed poise, accuracy, and leadership that elevated the Falcons’ entire offense.

Patrick Mahomes, QB, Kansas City Chiefs

Patrick Mahomes bounced back after a slow start, igniting the Chiefs’ offense with a 56-yard drive capped by a touchdown to JuJu Smith-Schuster. From there, he rolled to 270 passing yards and four touchdowns, showcasing his usual brilliance. The performance reminded everyone how quickly Mahomes can flip a game. Kansas City leaned on him to regain control, and he delivered in full.